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Title:

Hyperkalemia in patients treated with endoradiotherapy combined with amino acid infusion is associated with severe metabolic acidosis.

Document type:
Journal Article; Journal Article
Author(s):
Pfob, Christian H; Eiber, Matthias; Luppa, Peter; Maurer, Florian; Maurer, Tobias; Tauber, Robert; D'Alessandria, Calogero; Feuerecker, Benedikt; Scheidhauer, Klemens; Ott, Armin; Heemann, Uwe; Schwaiger, Markus; Schmaderer, Christoph
Abstract:
Amino acid co-infusion for renal protection in endoradiotherapy (ERT) applied as prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT) or peptide receptor radionuclide therapy (PRRT) has been shown to cause severe hyperkalemia. The pathophysiology behind the rapid development of hyperkalemia is not well understood. We hypothesized that the hyperkalemia should be associated with metabolic acidosis.Twenty-two patients underwent ERT. Prior to the first cycle, excretory kidney...     »
Journal title abbreviation:
EJNMMI Res
Year:
2018
Journal volume:
8
Journal issue:
1
Pages contribution:
17
Language:
eng
Fulltext / DOI:
doi:10.1186/s13550-018-0370-z
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29488080
Print-ISSN:
2191-219X
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann); Institut für Klinische Chemie und Pathobiochemie; Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Nuklearmedizin; Urologische Klinik und Poliklinik
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