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Title:

A Multiphysics Approach for Modeling Early Atherosclerosis

Document type:
Zeitschriftenaufsatz
Author(s):
Thon, M.P., Hemmler, A., Glinzer, A., Mayr, M., Wildgruber, M., Zernecke-Madsen, A., Gee, M.W.
Abstract:
This work is devoted to the development of a mathematical model of the early stages of atherosclerosis incorporating processes of all time scales of the disease and to show their interactions. The cardiovascular mechanics is modeled by a fluid-structure interaction approach coupling a non-Newtonian fluid to a hyperelastic solid undergoing anisotropic growth and a change of its constitutive equation. Additionally, the transport of low-density lipoproteins and its penetration through the...     »
Keywords:
atherosclerosis, multiphysics, fluid-structure interaction, growth and remodeling, cardiovascular mechanics, hemodynamics, pulsatile flow
Journal title:
Biomechanics and Modeling in Mechanobiology
Year:
2018
Journal volume:
17
Pages contribution:
617-644
Covered by:
Scopus
Fulltext / DOI:
doi:10.1007/s10237-017-0982-7
Notes:
This is a pre-print of an article published in Biomechanics and Modeling in Mechanobiology. The final authenticated version is available online at: https://doi.org/10.1007/s10237-017-0982-7 .
Status:
Verlagsversion / published
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