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Title:

Therapeutic potential of endogenous stem cells and cellular factors for scar-free skin regeneration.

Document type:
Journal Article; Review
Author(s):
Giri, Shibashish; Machens, Hans-Günther; Bader, Augustinus
Abstract:
Injured human skin fails to regenerate, resulting in scar formation. Annually, 100 million new skin-scarring incidents, occurring as a result of surgery, disease, burns, or sports-related damage, remain untreated. Here, we review knowledge gained from scar-free experimental animal models that have natural regenerative mechanisms for scar-free skin recovery. We also focus on the unique role of endogenous stem cells and other cellular and molecular factors, including the balance of the transformin...     »
Journal title abbreviation:
Drug Discov Today
Year:
2019
Journal volume:
24
Journal issue:
1
Pages contribution:
69-84
Fulltext / DOI:
doi:10.1016/j.drudis.2018.10.014
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30408529
Print-ISSN:
1359-6446
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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