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Titel:

Cytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases.

Dokumenttyp:
Article; Journal Article
Autor(en):
Lepennetier, Gildas; Hracsko, Zsuzsanna; Unger, Marina; Van Griensven, Martijn; Grummel, Verena; Krumbholz, Markus; Berthele, Achim; Hemmer, Bernhard; Kowarik, Markus C
Abstract:
BACKGROUND: Cytokines play multiple roles during neuro-inflammatory processes and several cytokines have been studied in the context of specific diseases. This study provides a comprehensive picture of cerebrospinal fluid (CSF) changes during neuro-inflammation by analyzing multiple cytokines in combination with immune cell subsets and standard CSF parameters. METHODS: Using multiplex assays, we simultaneously measured 36 cytokines (CCL1-3, CCL7, CCL8, CCL11, CCL13, CCL19, CCL20, CCL22-27, CXCL1...     »
Zeitschriftentitel:
J Neuroinflammation
Jahr:
2019
Band / Volume:
16
Heft / Issue:
1
Volltext / DOI:
doi:10.1186/s12974-019-1601-6
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31727097
Print-ISSN:
1742-2094
TUM Einrichtung:
Klinik und Poliklinik für Unfallchirurgie; Molekulare Immunologie (Prof. Knolle); Neurologische Klinik und Poliklinik
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