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Titel:

Can we predict cognitive decline after initial diagnosis of multiple sclerosis? Results from the German National early MS cohort (KKNMS).

Dokumenttyp:
Journal Article
Autor(en):
Johnen, Andreas; Bürkner, Paul-Christian; Landmeyer, Nils C; Ambrosius, Björn; Calabrese, Pasquale; Motte, Jeremias; Hessler, Nicole; Antony, Gisela; König, Inke R; Klotz, Luisa; Hoshi, Muna-Miriam; Aly, Lilian; Groppa, Sergiu; Luessi, Felix; Paul, Friedemann; Tackenberg, Björn; Bergh, Florian Then; Kümpfel, Tania; Tumani, Hayrettin; Stangel, Martin; Weber, Frank; Bayas, Antonios; Wildemann, Brigitte; Heesen, Christoph; Zettl, Uwe K; Zipp, Frauke; Hemmer, Bernhard; Meuth, Sven G; Gold, Ralf; Wie...     »
Abstract:
BACKGROUND: Cognitive impairment (CI) affects approximately one-third of the patients with early multiple sclerosis (MS) and clinically isolated syndrome (CIS). Little is known about factors predicting CI and progression after initial diagnosis. METHODS: Neuropsychological screening data from baseline and 1-year follow-up of a prospective multicenter cohort study (NationMS) involving 1123 patients with newly diagnosed MS or CIS were analyzed. Employing linear multilevel models, we investigated w...     »
Zeitschriftentitel:
J Neurol
Jahr:
2019
Band / Volume:
266
Heft / Issue:
2
Seitenangaben Beitrag:
386-397
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00415-018-9142-y
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30515631
Print-ISSN:
0340-5354
TUM Einrichtung:
Molekulare Immunologie (Prof. Knolle); Neurologische Klinik und Poliklinik
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