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Titel:

The Interleukin (IL)-23/T helper (Th)17 Axis in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis.

Dokumenttyp:
Article; Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Hiltensperger, Michael; Korn, Thomas
Abstract:
T helper (Th)17 cells are responsible for host defense against fungi and certain extracellular bacteria but have also been reported to play a role in a variety of autoimmune diseases. Th17 cells respond to environmental cues, are very plastic, and might also be involved in tissue homeostasis and regeneration. The imprinting of pathogenic properties in Th17 cells in autoimmunity seems highly dependent on interleukin (IL)-23. Since Th17 cells were first described in experimental autoimmune encepha...     »
Zeitschriftentitel:
Cold Spring Harb Perspect Med
Jahr:
2018
Band / Volume:
8
Heft / Issue:
1
Volltext / DOI:
doi:10.1101/cshperspect.a029637
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29101111
TUM Einrichtung:
Molekulare Immunologie (Prof. Knolle); Neurologische Klinik und Poliklinik
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