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Title:

Fat Mass and Obesity-Related Gene Variants rs9939609 and rs7185735 are Associated with Second-Generation Antipsychotic-Induced Weight Gain.

Document type:
Journal Article; Journal Article
Author(s):
Schröder, Charlotte; Czerwensky, Fabian; Leucht, Stefan; Steimer, Werner
Abstract:
INTRODUCTION: Weight gain is a limiting and frequent adverse effect of second-generation antipsychotic therapy. Identifying genetic risk factors would significantly improve pharmacotherapy. METHODS: We focused on rs7185735 and rs9939609, 2 common single nucleotide polymorphisms of the fat mass and obesity-associated (FTO) gene reported to be associated with obesity. Three-hundred fifty Caucasian inpatients were included in a naturalistic study. RESULTS: After 4 weeks of treatment, we did not obs...     »
Journal title abbreviation:
Pharmacopsychiatry
Year:
2019
Journal volume:
52
Journal issue:
1
Pages contribution:
16-23
Language:
eng
Fulltext / DOI:
doi:10.1055/s-0043-125392
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29334686
Print-ISSN:
0176-3679
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie; Klinik und Poliklinik für Psychiatrie und Psychotherapie
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