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Titel:

Fat Mass and Obesity-Related Gene Variants rs9939609 and rs7185735 are Associated with Second-Generation Antipsychotic-Induced Weight Gain.

Dokumenttyp:
Journal Article; Journal Article
Autor(en):
Schröder, Charlotte; Czerwensky, Fabian; Leucht, Stefan; Steimer, Werner
Abstract:
INTRODUCTION: Weight gain is a limiting and frequent adverse effect of second-generation antipsychotic therapy. Identifying genetic risk factors would significantly improve pharmacotherapy. METHODS: We focused on rs7185735 and rs9939609, 2 common single nucleotide polymorphisms of the fat mass and obesity-associated (FTO) gene reported to be associated with obesity. Three-hundred fifty Caucasian inpatients were included in a naturalistic study. RESULTS: After 4 weeks of treatment, we did not obs...     »
Zeitschriftentitel:
Pharmacopsychiatry
Jahr:
2019
Band / Volume:
52
Heft / Issue:
1
Seitenangaben Beitrag:
16-23
Sprache:
eng
Volltext / DOI:
doi:10.1055/s-0043-125392
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29334686
Print-ISSN:
0176-3679
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie; Klinik und Poliklinik für Psychiatrie und Psychotherapie
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