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Titel:

Occlusive dressing-induced secretomes influence the migration and proliferation of mesenchymal stem cells and fibroblasts differently.

Dokumenttyp:
Journal Article
Autor(en):
Cerny, Michael K; Hopfner, Ursula; Kirsch, Manuela; Haas, Elisabeth-Maria; Wu, Fan; Giunta, Riccardo; Machens, Hans-Guenther; Duscher, Dominik; Erne, Holger; Schilling, Arndt F
Abstract:
Fingertip injuries treated with occlusive dressings (ODs) lead to nearly scar-free, functionally, and aesthetically pleasing results. We hypothesized that paracrine factors in the wound fluid (secretome) may influence migration and proliferation of mesenchymal stem cells (MSCs) and fibroblasts and modulate the wound-healing process.We could collect wound fluid samples from 4 fingertip injuries and 7 split skin donor sites at the 5th day during dressing change. Blood serum samples served as contr...     »
Zeitschriftentitel:
Eur J Med Res
Jahr:
2018
Band / Volume:
23
Heft / Issue:
1
Seitenangaben Beitrag:
60
Sprache:
eng
Volltext / DOI:
doi:10.1186/s40001-018-0357-2
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30585140
Print-ISSN:
0949-2321
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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