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Title:

Development of photosynthetic sutures for the local delivery of oxygen and recombinant growth factors in wounds.

Document type:
Journal Article
Author(s):
Centeno-Cerdas, Carolina; Jarquín-Cordero, Montserrat; Chávez, Myra Noemi; Hopfner, Ursula; Holmes, Christopher; Schmauss, Daniel; Machens, Hans-Günther; Nickelsen, Jörg; Egaña, José Tomás
Abstract:
Surgical sutures represent the gold standard for wound closure, however, their main purpose is still limited to a mechanical function rather than playing a bioactive role. Since oxygen and pro-regenerative growth factors have been broadly described as key players for the healing process, in this study we evaluated the feasibility of generating photosynthetic sutures that, in addition to mechanical fixation, could locally and stably release oxygen and recombinant human growth factors (VEGF, PDGF-...     »
Journal title abbreviation:
Acta Biomater
Year:
2018
Journal volume:
81
Pages contribution:
184-194
Language:
eng
Fulltext / DOI:
doi:10.1016/j.actbio.2018.09.060
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30287280
Print-ISSN:
1742-7061
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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