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Titel:

Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes.

Dokumenttyp:
Journal Article
Autor(en):
Skrzypczyk, Aniela; Kehr, Stephanie; Krystel, Ilona; Bernhart, Stephan H; Giri, Shibashish; Bader, Augustinus; Stadler, Peter F
Abstract:
Recent advances in the stem cell field allow to obtain many human tissues in vitro. However, hepatic differentiation of induced pluripotent stem cells (iPSCs) still remains challenging. Hepatocyte-like cells (HLCs) obtained after differentiation resemble more fetal liver hepatocytes. MicroRNAs (miRNA) play an important role in the differentiation process. Here, we analysed noncoding RNA profiles from the last stages of differentiation and compare them to hepatocytes. Our results show that HLCs m...     »
Zeitschriftentitel:
Stem Cells Int
Jahr:
2018
Band / Volume:
2018
Seitenangaben Beitrag:
5692840
Sprache:
eng
Volltext / DOI:
doi:10.1155/2018/5692840
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30210551
Print-ISSN:
1687-966X
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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