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Title:

Characterization of Bulk Phosphatidylcholine Compositions in Human Plasma Using Side-Chain Resolving Lipidomics.

Document type:
Journal Article
Author(s):
Quell, Jan D; Römisch-Margl, Werner; Haid, Mark; Krumsiek, Jan; Skurk, Thomas; Halama, Anna; Stephan, Nisha; Adamski, Jerzy; Hauner, Hans; Mook-Kanamori, Dennis; Mohney, Robert P; Daniel, Hannelore; Suhre, Karsten; Kastenmüller, Gabi
Abstract:
Kit-based assays, such as AbsoluteIDQTM p150, are widely used in large cohort studies and provide a standardized method to quantify blood concentrations of phosphatidylcholines (PCs). Many disease-relevant associations of PCs were reported using this method. However, their interpretation is hampered by lack of functionally-relevant information on the detailed fatty acid side-chain compositions as only the total number of carbon atoms and double bonds is identified by the kit. To enable more subs...     »
Journal title abbreviation:
Metabolites
Year:
2019
Journal volume:
9
Journal issue:
6
Fulltext / DOI:
doi:10.3390/metabo9060109
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31181753
TUM Institution:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin
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