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Title:

Quantitation of 5-methyltetraydrofolic acid in plasma for determination of folate status and clinical studies by stable isotope dilution assays.

Document type:
Journal Article; Article
Author(s):
Striegel, Lisa; Brandl, Beate; Kopp, Markus; Sam, Lukas; Skurk, Thomas; Rychlik, Michael
Abstract:
Folates play a key role in the prevention of neural tube defects in newborns. Thus, it is important to reliably determine the bioavailability of folates from various foods. Accurate analytical methods are essential for quantifying blood-folates, especially in human studies. Here, we present the development and validation of a sensitive method using stable isotope dilution liquid chromatography coupled with mass spectrometry for determining various folates in plasma. Moreover, this study reports...     »
Journal title abbreviation:
PLoS ONE
Year:
2019
Journal volume:
14
Journal issue:
2
Pages contribution:
e0212255
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0212255
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30789924
Print-ISSN:
1932-6203
TUM Institution:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin
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