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Title:

Moving Second Courses of Radiotherapy Forward: Early Re-Irradiation After Surgical Resection for Recurrent Gliomas Improves Efficacy With Excellent Tolerability.

Document type:
Journal Article
Author(s):
Combs, Stephanie E; Kessel, Kerstin A; Hesse, Josefine; Straube, Christoph; Zimmer, Claus; Schmidt-Graf, Friederike; Schlegel, Jürgen; Gempt, Jens; Meyer, Bernhard
Abstract:
BACKGROUND: Generally, re-irradiation (Re-RT) is offered to patients with glioma recurrences with macroscopic lesions. Results are discussed controversially, and some centers postulate limited benefit of Re-RT. Re-RT is generally offered to tumors up to 4 cm in diameter. Re-resection is also discussed controversially; however, recent studies have shown significant benefit. OBJECTIVE: To combine proactive re-resection and early Re-RT in patients with recurrent glioma. METHODS: We included 108 pa...     »
Journal title abbreviation:
Neurosurgery
Year:
2018
Journal volume:
83
Journal issue:
6
Pages contribution:
1241-1248
Language:
eng
Fulltext / DOI:
doi:10.1093/neuros/nyx629
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29462372
Print-ISSN:
0148-396X
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Neurochirurgische Klinik und Poliklinik; Neurologische Klinik und Poliklinik
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