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Title:

Bone Marrow-Derived Mesenchymal Stromal Cells Enhanced by Platelet-Rich Plasma Maintain Adhesion to Scaffolds in Arthroscopic Simulation.

Document type:
Journal Article
Author(s):
Hoberman, Alexander R; Cirino, Carl; McCarthy, Mary Beth; Cote, Mark P; Pauzenberger, Leo; Beitzel, Knut; Mazzocca, Augustus D; Dyrna, Felix
Abstract:
To assess the response of bone marrow-derived mesenchymal stromal cells (bMSCs) enhanced by platelet-rich plasma (PRP) in the setting of a normal human tendon (NHT), a demineralized bone matrix (DBM), and a fibrin scaffold (FS) with simulated arthroscopic mechanical washout stress.Bone marrow was aspirated from the humeral head and concentrated. BMSCs were counted, plated, and grown to confluence. Cells were seeded onto 3 different scaffolds: (1) NHT, (2) DBM, and (3) FS. Each scaffold was treat...     »
Journal title abbreviation:
Arthroscopy
Year:
2018
Journal volume:
34
Journal issue:
3
Pages contribution:
872-881
Language:
eng
Fulltext / DOI:
doi:10.1016/j.arthro.2017.08.291
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29146168
Print-ISSN:
0749-8063
TUM Institution:
Fachgebiet Sportorthopädie (Prof. Imhoff)
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