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Titel:

Sleep disturbance by pramipexole is modified by Meis1 in mice.

Dokumenttyp:
Journal Article
Autor(en):
Salminen, Aaro V; Schormair, Barbara; Flachskamm, Cornelia; Torres, Miguel; Müller-Myhsok, Bertram; Kimura, Mayumi; Winkelmann, Juliane
Abstract:
Meis homeobox 1 (Meis1) is a transcription factor functioning in the development of the nervous system and the cardiovascular system. Both common and rare variants within the gene have been associated with restless legs syndrome (RLS), while its association with symptoms of insomnia has also been discovered recently. RLS is associated with sleep disturbances, and while Meis1 haploinsufficiency is one of the most promising strategies for an RLS animal model, sleep phenotyping of Meis1 knockout mi...     »
Zeitschriftentitel:
J Sleep Res
Jahr:
2018
Band / Volume:
27
Heft / Issue:
4
Seitenangaben Beitrag:
e12557
Sprache:
eng
Volltext / DOI:
doi:10.1111/jsr.12557
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28695622
Print-ISSN:
0962-1105
TUM Einrichtung:
Institut für Humangenetik; Lehrstuhl für Neurogenetik (Prof. Winkelmann)
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