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Titel:

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Dokumenttyp:
Journal Article; Review
Autor(en):
Fuchs, Helmut; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V; Becker, Lore; Calzada-Wack, Julia; Cho, Yi-Li; Garrett, Lillian; Hölter, Sabine M; Irmler, Martin; Kistler, Martin; Kraiger, Markus; Mayer-Kuckuk, Philipp; Moreth, Kristin; Rathkolb, Birgit; Rozman, Jan; da Silva Buttkus, Patricia; Treise, Irina; Zimprich, Annemarie; Gampe, Kristine; Hutterer, Christine; Stöger, Claudia; Leuchtenberger, Stefanie; Maier, Holger; Miller, Manuel; Scheideler, Angelika; Wu, Moya; Beckers, Johannes; Bekere...     »
Abstract:
Since decades, model organisms have provided an important approach for understanding the mechanistic basis of human diseases. The German Mouse Clinic (GMC) was the first phenotyping facility that established a collaboration-based platform for phenotype characterization of mouse lines. In order to address individual projects by a tailor-made phenotyping strategy, the GMC advanced in developing a series of pipelines with tests for the analysis of specific disease areas. For a general broad analysi...     »
Zeitschriftentitel:
Behav Brain Res
Jahr:
2018
Band / Volume:
352
Seitenangaben Beitrag:
187-196
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.bbr.2017.09.048
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28966146
Print-ISSN:
0166-4328
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Molekulare Allergologie (Prof. Schmidt-Weber)
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