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Titel:

Immunization with a recombinant fusion protein protects mice against Helicobacter pylori infection.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Ghasemi, Amir; Mohammad, Nazanin; Mautner, Josef; Taghipour Karsabet, Mehrnaz; Amani, Jafar; Ardjmand, Abolfazl; Vakili, Zarichehr
Abstract:
More than 50% of the world's population is infected with the bacterium Helicobacter pylori. If left untreated, infection with H. pylori can cause chronic gastritis and peptic ulcer disease, which may progress into gastric cancer. Owing to the limited efficacy of anti-H. pylori antibiotic therapy in clinical practice, the development of a protective vaccine to combat this pathogen has been a tempting goal for several years. In this study, a chimeric gene coding for the antigenic parts of H. pylor...     »
Zeitschriftentitel:
Vaccine
Jahr:
2018
Band / Volume:
36
Heft / Issue:
34
Seitenangaben Beitrag:
5124-5132
Volltext / DOI:
doi:10.1016/j.vaccine.2018.07.033
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30041879
Print-ISSN:
0264-410X
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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