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Titel:

Outcome of hematopoietic cell transplantation for DNA double-strand break repair disorders.

Dokumenttyp:
Journal Article; Article
Autor(en):
Slack, James; Albert, Michael H; Balashov, Dmitry; Belohradsky, Bernd H; Bertaina, Alice; Bleesing, Jack; Booth, Claire; Buechner, Jochen; Buckley, Rebecca H; Ouachée-Chardin, Marie; Deripapa, Elena; Drabko, Katarzyna; Eapen, Mary; Feuchtinger, Tobias; Finocchi, Andrea; Gaspar, H Bobby; Ghosh, Sujal; Gillio, Alfred; González-Granado, Luis I; Grunebaum, Eyal; Güngör, Tayfun; Heilmann, Carsten; Helminen, Merja; Higuchi, Kohei; Imai, Kohsuke; Kalwak, Krzysztof; Kanazawa, Nubuo; Karasu, Gülsün; Kucu...     »
Abstract:
Rare DNA breakage repair disorders predispose to infection and lymphoreticular malignancies. Hematopoietic cell transplantation (HCT) is curative, but coadministered chemotherapy or radiotherapy is damaging because of systemic radiosensitivity. We collected HCT outcome data for Nijmegen breakage syndrome, DNA ligase IV deficiency, Cernunnos-XRCC4-like factor (Cernunnos-XLF) deficiency, and ataxia-telangiectasia (AT).Data from 38 centers worldwide, including indication, donor, conditioning regime...     »
Zeitschriftentitel:
J Allergy Clin Immunol
Jahr:
2018
Band / Volume:
141
Heft / Issue:
1
Seitenangaben Beitrag:
322-328.e10
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jaci.2017.02.036
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28392333
Print-ISSN:
0091-6749
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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