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Titel:

High NOTCH1 mRNA Expression Is Associated with Better Survival in HNSCC.

Dokumenttyp:
Journal Article
Autor(en):
Wirth, Markus; Jira, Daniel; Ott, Armin; Piontek, Guido; Pickhard, Anja
Abstract:
The clinical impact of the expression of NOTCH1 signaling components in squamous cell carcinoma of the pharynx and larynx has only been evaluated in subgroups. The aim of this study was therefore to evaluate NOTCH1 expression in head and neck squamous cell cancer (HNSCC) patient tissue and cell lines. We analyzed tissue from 195 HNSCCs and tissue from 30 normal patients for mRNA expression of NOTCH1, NOTCH3, HES1, HEY1, and JAG1 using quantitative real-time PCR. Association of expression results...     »
Zeitschriftentitel:
Int J Mol Sci
Jahr:
2018
Band / Volume:
19
Heft / Issue:
3
Volltext / DOI:
doi:10.3390/ijms19030830
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29533972
Print-ISSN:
1422-0067
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik; Institut für Medizinische Statistik und Epidemiologie
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