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Titel:

Mortality prediction in stable hemodialysis patients is refined by YKL-40, a 40-kDa glycoprotein associated with inflammation.

Dokumenttyp:
Journal Article; Journal Article
Autor(en):
Lorenz, Georg; Schmalenberg, Michael; Kemmner, Stephan; Haller, Bernhard; Steubl, Dominik; Pham, Dang; Schreiegg, Anita; Bachmann, Quirin; Schmidt, Alina; Haderer, Sandra; Huber, Monika; Angermann, Susanne; Günthner, Roman; Braunisch, Matthias; Hauser, Christine; Reichelt, Anna-Lena; Matschkal, Julia; Suttmann, Yana; Moog, Philipp; Stock, Konrad; Küchle, Claudius; Thürmel, Klaus; Renders, Lutz; Bauer, Axel; Baumann, Marcus; Heemann, Uwe; Luppa, Peter B; Schmaderer, Christoph
Abstract:
Chronic inflammation contributes to increased mortality in hemodialysis (HD) patients. YKL-40 is a novel marker of inflammation, tissue remodeling, and highly expressed in macrophages inside vascular lesions. Elevated levels of YKL-40 have been reported for HD patients but how it integrates into the proinflammatory mediator network as a predictor of mortality remains elusive. We studied serum YKL-40, Interleukin-6 (IL-6), high-sensitivity C-reactive protein, monocyte chemotactic protein-1 (MCP-1...     »
Zeitschriftentitel:
Kidney Int
Jahr:
2018
Band / Volume:
93
Heft / Issue:
1
Seitenangaben Beitrag:
221-230
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.kint.2017.07.010
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28941940
Print-ISSN:
0085-2538
TUM Einrichtung:
Fachgebiet Nephrologie (Prof. Heemann); Institut für Klinische Chemie und Pathobiochemie; Institut für Medizinische Statistik und Epidemiologie
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