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Title:

The effect of attenuation map, scatter energy window width, and volume of interest on the calibration factor calculation in quantitative 177Lu SPECT imaging: Simulation and phantom study.

Document type:
Journal Article
Author(s):
Karimi Ghodoosi, Elham; D'Alessandria, Calogero; Li, Ye; Bartel, Alexandra; Köhner, Markus; Höllriegl, Vera; Navab, Nassir; Eiber, Matthias; Li, Wei Bo; Frey, Eric; Ziegler, Sibylle
Abstract:
PURPOSE: The objective of this study was to evaluate the image degrading factors in quantitative 177Lu SPECT imaging when using both main gamma photopeak energies. METHODS: Phantom measurements with two different vials containing various calibrated activities in air or water were performed to derive a mean calibration factor (CF) for large and small volumes of interest (VOIs). In addition, Monte Carlo simulations were utilized to investigate the effect of scatter energy window width, scatter cor...     »
Journal title abbreviation:
Phys Med
Year:
2018
Journal volume:
56
Pages contribution:
74-80
Fulltext / DOI:
doi:10.1016/j.ejmp.2018.11.009
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30527092
Print-ISSN:
1120-1797
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin
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