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Titel:

Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumour-associated factors in serous ovarian cancer.

Dokumenttyp:
Journal Article
Autor(en):
Wang, Ping; Magdolen, Viktor; Seidl, Christof; Dorn, Julia; Drecoll, Enken; Kotzsch, Matthias; Yang, Feng; Schmitt, Manfred; Schilling, Oliver; Rockstroh, Anja; Clements, Judith Ann; Loessner, Daniela
Abstract:
BACKGROUND: Tissue kallikrein-related peptidases 4, 5, 6 and 7 (KLK4-7) strongly increase the malignancy of ovarian cancer cells. Deciphering their downstream effectors, we aimed at finding new potential prognostic biomarkers and treatment targets for ovarian cancer patients. KLK4-7-transfected (OV-KLK4-7) and vector-control OV-MZ-6 (OV-VC) ovarian cancer cells were established to select differentially regulated factors. METHODS: With three independent approaches, PCR arrays, genome-wide microar...     »
Zeitschriftentitel:
Br J Cancer
Jahr:
2018
Band / Volume:
119
Heft / Issue:
7
Seitenangaben Beitrag:
1-9
Sprache:
eng
Volltext / DOI:
doi:10.1038/s41416-018-0260-1
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30287916
Print-ISSN:
0007-0920
TUM Einrichtung:
Frauenklinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin
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