User: Guest  Login
Title:

Comparison of the Hydroxylase Inhibitor Dimethyloxalylglycine and the Iron Chelator Deferoxamine in Diabetic and Aged Wound Healing.

Document type:
Comparative Study; Journal Article
Author(s):
Duscher, Dominik; Januszyk, Michael; Maan, Zeshaan N; Whittam, Alexander J; Hu, Michael S; Walmsley, Graham G; Dong, Yixiao; Khong, Sacha M; Longaker, Michael T; Gurtner, Geoffrey C
Abstract:
A hallmark of diabetes mellitus is the breakdown of almost every reparative process in the human body, leading to critical impairments of wound healing. Stabilization and activity of the transcription factor hypoxia-inducible factor (HIF)-1? is impaired in diabetes, leading to deficits in new blood vessel formation in response to injury. In this article, the authors compare the effectiveness of two promising small-molecule therapeutics, the hydroxylase inhibitor dimethyloxalylglycine and the iro...     »
Journal title abbreviation:
Plast Reconstr Surg
Year:
2017
Journal volume:
139
Journal issue:
3
Pages contribution:
695e-706e
Language:
eng
Fulltext / DOI:
doi:10.1097/PRS.0000000000003072
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28234841
Print-ISSN:
0032-1052
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
 BibTeX