Stiegler, Sandrine C.;Rübbelke, Martin;Korotkov, Vadim S.;Weiwad, Matthias;John, Christine;Fischer, Gunter;Sieber, Stephan A.;Sattler, Michael;Buchner, Johannes
A chemical compound inhibiting the Aha1–Hsp90 chaperone complex
Journal of Biological Chemistry
2017
292
41
17073-17083

Wright, M. H.;Tao, Y.;Drechsel, J.;Krysiak, J.;Chamni, S.;Weigert-Munoz, A.;Harvey, N. L.;Romo, D.;Sieber, S. A.
Quantitative chemoproteomic profiling reveals multiple target interactions of spongiolactone derivatives in leukemia cells
Chemical Communications
2017
53
95
12818-12821

Wright, Megan H.;Fetzer, Christian;Sieber, Stephan A.
Chemical Probes Unravel an Antimicrobial Defense Response Triggered by Binding of the Human Opioid Dynorphin to a Bacterial Sensor Kinase
Journal of the American Chemical Society
2017
139
17
6152-6159

Krysiak, Joanna;Stahl, Matthias;Vomacka, Jan;Fetzer, Christian;Lakemeyer, Markus;Fux, Anja;Sieber, Stephan A.
Quantitative Map of β-Lactone-Induced Virulence Regulation
Journal of Proteome Research
2017
16
3
1180-1192

Stahl, Matthias;Sieber, Stephan A
An amino acid domino effect orchestrates ClpP's conformational states
Current Opinion in Chemical Biology
2017
40
102-110

Zhu, Mingzhao;Harshbarger, Wayne D.;Robles, Omar;Krysiak, Joanna;Hull, Kenneth G.;Cho, Sung Wook;Richardson, Robyn D.;Yang, Yanyan;Garcia, Andres;Spiegelman, Lindsey;Ramirez, Bianca;Wilson, Christopher T.;Yau, Ju Anne;Moore, James T.;Walker, Caitlen B.;Sacchettini, James C.;Liu, Wenshe R.;Sieber, Stephan A.;Smith, Jeffrey W.;Romo, Daniel
A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids
Bioorganic & Medicinal Chemistry
2017
25
11
2901-2916

Lehmann, Johannes;Cheng, Tan-Yun;Aggarwal, Anup;Park, Annie S.;Zeiler, Evelyn;Raju, Ravikiran M.;Akopian, Tatos;Kandror, Olga;Sacchettini, James C.;Moody, D. Branch;Rubin, Eric J.;Sieber, Stephan A.
An Antibacterial β-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis
Angewandte Chemie International Edition
2017
57
1
348-353

Fetzer, Christian;Korotkov, Vadim S.;Thänert, Robert;Lee, Kyu Myung;Neuenschwander, Martin;von Kries, Jens Peter;Medina, Eva;Sieber, Stephan A.
A Chemical Disruptor of the ClpX Chaperone Complex Attenuates the Virulence of Multidrug-Resistant Staphylococcus aureus
Angewandte Chemie International Edition
2017
56
49
15746-15750

Fetzer, Christian
Virulence Attenuation through Chemical and Genetic Manipulation of the Staphylococcus aureus ClpXP Protease
2017
Dissertation
125 Seiten

Bolz, Christian;Bach, Nina C.;Meyer, Hannelore;Müller, Gerhard;Dawidowski, Maciej;Popowicz, Grzegorz;Sieber, Stephan A.;Skerra, Arne;Gerhard, Markus
Comparison of enzymatic properties and small molecule inhibition of γ–glutamyltranspeptidases from pathogenic and commensal bacteria
Biological Chemistry
2017
398
3