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Titel:

Adjuvant stereotactic fractionated radiotherapy to the resection cavity in recurrent glioblastoma - the GlioCave study (NOA 17 - ARO 2016/3 - DKTK ROG trial).

Dokumenttyp:
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Autor(en):
Straube, Christoph; Scherb, Hagen; Gempt, Jens; Kirschke, Jan; Zimmer, Claus; Schmidt-Graf, Friederike; Meyer, Bernhard; Combs, Stephanie E
Abstract:
BACKGROUND: Glioblastoma relapses in the vast majority of cases within 1 year. Maximum safe resection of the recurrent glioblastoma can be offered in some cases. Re-irradiation has been established for the treatment of recurrent glioblastoma, too. In both cases, adjuvant treatment, mostly using temozolomide, can improve PFS and OS after these interventions. However, combining gross tumor resection and adjuvant re-radiotherapy to the resection cavity has not been tested so far. METHODS/DESIGN: In...     »
Zeitschriftentitel:
BMC Cancer
Jahr:
2018
Band / Volume:
18
Heft / Issue:
1
Seitenangaben Beitrag:
15
Sprache:
eng
Volltext / DOI:
doi:10.1186/s12885-017-3928-7
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29298660
TUM Einrichtung:
Fachgebiet Neuroradiologie (Prof. Zimmer); Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Neurochirurgische Klinik und Poliklinik; Neurologische Klinik und Poliklinik
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