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Titel:

Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells .

Dokumenttyp:
Journal Article; Article
Autor(en):
Salvermoser, Johanna; van Blijswijk, Janneke; Papaioannou, Nikos E; Rambichler, Stephan; Pasztoi, Maria; Pakalni?kyt?, Dalia; Rogers, Neil C; Keppler, Selina J; Straub, Tobias; Reis E Sousa, Caetano; Schraml, Barbara U
Abstract:
Conventional dendritic cells (cDCs) are versatile activators of immune responses that develop as part of the myeloid lineage downstream of hematopoietic stem cells. We have recently shown that in mice precursors of cDCs, but not of other leukocytes, are marked by expression of DNGR-1/CLEC9A. To genetically deplete DNGR-1-expressing cDC precursors and their progeny, we crossed mice to Rosa-lox-STOP-lox-diphtheria toxin (DTA) mice. These mice develop signs of age-dependent myeloproliferative dise...     »
Zeitschriftentitel:
Front Immunol
Jahr:
2018
Band / Volume:
9
Seitenangaben Beitrag:
699
Volltext / DOI:
doi:10.3389/fimmu.2018.00699
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29713321
Print-ISSN:
1664-3224
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie
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