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Titel:

MEIS1 variant as a determinant of autonomic imbalance in Restless Legs Syndrome.

Dokumenttyp:
journal article
Autor(en):
Thireau, Jérôme; Farah, Charlotte; Molinari, Nicolas; Bouilloux, Fabrice; Torreilles, Lucas; Winkelmann, Juliane; Scholz, Sabine; Richard, Sylvain; Dauvilliers, Yves; Marmigère, Frédéric
Abstract:
Restless Legs Syndrome (RLS) is a genetically complex neurological disorder in which overlapping genetic risk factors may contribute to the diversity and heterogeneity of the symptoms. The main goal of the study was to investigate, through analysis of heart rate variability (HRV), whether in RLS patients the MEIS1 polymorphism at risk influences the sympathovagal regulation in different sleep stages. Sixty-four RLS patients with periodic leg movement index above 15 per hour, and 38 controls unde...     »
Zeitschriftentitel:
Sci Rep
Jahr:
2017
Band / Volume:
7
Seitenangaben Beitrag:
46620
Sprache:
eng
Volltext / DOI:
doi:10.1038/srep46620
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28425489
TUM Einrichtung:
Klinik und Poliklinik für Neurologie
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