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Titel:

Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Schulte, Eva C; Altmaier, Elisabeth; Berger, Hannah S; Do, Kieu Trinh; Kastenmüller, Gabi; Wahl, Simone; Adamski, Jerzy; Peters, Annette; Krumsiek, Jan; Suhre, Karsten; Haslinger, Bernhard; Ceballos-Baumann, Andres; Gieger, Christian; Winkelmann, Juliane
Abstract:
Serum metabolite profiling can be used to identify pathways involved in the pathogenesis of and potential biomarkers for a given disease. Both restless legs syndrome (RLS) and Parkinson`s disease (PD) represent movement disorders for which currently no blood-based biomarkers are available and whose pathogenesis has not been uncovered conclusively. We performed unbiased serum metabolite profiling in search of signature metabolic changes for both diseases.456 metabolites were quantified in serum s...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2016
Band / Volume:
11
Heft / Issue:
1
Seitenangaben Beitrag:
e0147129
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0147129
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26808974
Print-ISSN:
1932-6203
TUM Einrichtung:
Lehrstuhl für Neurogenetik (Prof. Winkelmann); Neurologische Klinik und Poliklinik
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