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Titel:

Hyaluronic acid facilitates chondrogenesis and matrix deposition of human adipose derived mesenchymal stem cells and human chondrocytes co-cultures.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article; Proceedings Paper
Autor(en):
Amann, Elisabeth; Wolff, Paul; Breel, Ernst; Van Griensven, Martijn; Balmayor, Elizabeth R
Abstract:
Clinical success on cartilage regeneration could be achieved by using available biomaterials and cell-based approaches. In this study, we have developed a composite gel based on collagen/hyaluronic acid (Coll-HA) as ideal, physiologically representative 3D support for in vitro chondrogenesis of human adipose-derived mesenchymal stem cells (hAMSCs) co-cultured with human articular chondrocytes (hAC). The incorporation of hyaluronic acid (HA) attempted to provide an additional stimulus to the hAMS...     »
Zeitschriftentitel:
Acta Biomater
Jahr:
2017
Band / Volume:
52
Seitenangaben Beitrag:
130-144
Volltext / DOI:
doi:10.1016/j.actbio.2017.01.064
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28131943
Print-ISSN:
1742-7061
TUM Einrichtung:
Klinik und Poliklinik für Unfallchirurgie
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