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Titel:

NOS1-, NOS3-, PIK3CA-, and MAPK-pathways in skin following radiation therapy.

Dokumenttyp:
Journal Article
Autor(en):
Koerdt, Steffen; Tanner, Nadine; Rommel, Niklas; Rohleder, Nils H; Frohwitter, Gesche; Ristow, Oliver; Wolff, Klaus-Dietrich; Kesting, Marco R
Abstract:
Essential molecular pathways such as the MAPK pathway, NO system, or the influence of PIK3CA as an oncogene are known to regulate fundamental signalling networks. However, few knowledge about their role in the occurrence of wound healing disorders (WHD) following radiation therapy (RT) exists. This study aims to evaluate the expression profiles of specific molecular pathway marker genes.Expression profiles of the genes encoding MAPK, NOS1, NOS3, and PIK3CA were analyzed, by RT-PCR, in specimens...     »
Zeitschriftentitel:
Biomark Res
Jahr:
2017
Band / Volume:
5
Seitenangaben Beitrag:
3
Sprache:
eng
Volltext / DOI:
doi:10.1186/s40364-017-0084-9
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28127430
TUM Einrichtung:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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