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Titel:

Denervation versus pre- and postsynaptic muscle immobilization: Effects On acetylcholine- and muscle-specific tyrosine kinase receptors.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Kramer, Christopher; Zoubaa, Saida; Kretschmer, Alexander; Jordan, Denis; Blobner, Manfred; Fink, Heidrun
Abstract:
Functional immobility of the diaphragm by mechanical ventilation impairs neuromuscular transmission and may result in ventilator-induced diaphragmatic dysfunction. We compared 3 diaphragmatic immobilization models with respect to their effects on expression of adult and fetal acetylcholine receptors (AChRs), muscle-specific receptor tyrosine kinase (MuSK), and muscle fiber morphology.Diaphragms of rats were immobilized by either: (1) phrenicotomy; (2) presynaptic tetrodotoxin nerve blockade; o...     »
Zeitschriftentitel:
Muscle Nerve
Jahr:
2017
Band / Volume:
55
Heft / Issue:
1
Seitenangaben Beitrag:
101-108
Sprache:
eng
Volltext / DOI:
doi:10.1002/mus.25159
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27104792
Print-ISSN:
0148-639X
TUM Einrichtung:
Klinik für Anästhesiologie (DHM)
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