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Title:

Clinical pharmacology and efficacy of sugammadex in the reversal of neuromuscular blockade.

Document type:
Journal Article; Review
Author(s):
Schaller, Stefan Josef; Lewald, Heidrun
Abstract:
Sugammadex is the first clinical representative of a class of drugs called steroidal muscle relaxant encapsulators. Due to its 1:1 binding of rocuronium or vecuronium, sugammadex can reverse any depth of neuromuscular block and has therefore revolutionized the way anesthetists think about drug reversal.This review gives an overview of the clinical pharmacology and efficacy of sugammadex in healthy patients as well as in patients with pre-existing diseases.After approval in Europe in 2008 and Asi...     »
Journal title abbreviation:
Expert Opin Drug Metab Toxicol
Year:
2016
Journal volume:
12
Journal issue:
9
Pages contribution:
1097-108
Language:
eng
Fulltext / DOI:
doi:10.1080/17425255.2016.1215426
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27463265
Print-ISSN:
1742-5255
TUM Institution:
Klinik für Anästhesiologie (DHM)
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