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Titel:

Clinical pharmacology and efficacy of sugammadex in the reversal of neuromuscular blockade.

Dokumenttyp:
Journal Article; Review
Autor(en):
Schaller, Stefan Josef; Lewald, Heidrun
Abstract:
Sugammadex is the first clinical representative of a class of drugs called steroidal muscle relaxant encapsulators. Due to its 1:1 binding of rocuronium or vecuronium, sugammadex can reverse any depth of neuromuscular block and has therefore revolutionized the way anesthetists think about drug reversal.This review gives an overview of the clinical pharmacology and efficacy of sugammadex in healthy patients as well as in patients with pre-existing diseases.After approval in Europe in 2008 and Asi...     »
Zeitschriftentitel:
Expert Opin Drug Metab Toxicol
Jahr:
2016
Band / Volume:
12
Heft / Issue:
9
Seitenangaben Beitrag:
1097-108
Sprache:
eng
Volltext / DOI:
doi:10.1080/17425255.2016.1215426
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27463265
Print-ISSN:
1742-5255
TUM Einrichtung:
Klinik für Anästhesiologie (DHM)
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