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Title:

Feasibility of structured endurance training and Mediterranean diet in BRCA1 and BRCA2 mutation carriers - an interventional randomized controlled multicenter trial (LIBRE-1).

Document type:
Journal Article; Multicenter Study; Randomized Controlled Trial; Article
Author(s):
Kiechle, Marion; Dukatz, Ricarda; Yahiaoui-Doktor, Maryam; Berling, Anika; Basrai, Maryam; Staiger, Vera; Niederberger, Uwe; Marter, Nicole; Lammert, Jacqueline; Grill, Sabine; Pfeifer, Katharina; Rhiem, Kerstin; Schmutzler, Rita K; Laudes, Matthias; Siniatchkin, Michael; Halle, Martin; Bischoff, Stephan C; Engel, Christoph
Abstract:
Women with pathogenic BRCA germline mutations have an increased risk for breast and ovarian cancer that seems to be modified by life-style factors. Though, randomized trials investigating the impact of lifestyle interventions on cancer prevention and prognosis in BRCA carriers are still missing.We implemented a multicenter, prospective randomized controlled trial in BRCA1/2 patients, comparing a lifestyle intervention group (IG) with a control group (CG) with the primary aim to prove feasibility...     »
Journal title abbreviation:
BMC Cancer
Year:
2017
Journal volume:
17
Journal issue:
1
Pages contribution:
752
Language:
eng
Fulltext / DOI:
doi:10.1186/s12885-017-3732-4
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29126396
TUM Institution:
Frauenklinik und Poliklinik; Poliklinik für Präventive und Rehabilitative Sportmedizin
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