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Titel:

Non-invasive assessment of inter-and intrapatient variability of integrin expression in metastasized prostate cancer by PET.

Dokumenttyp:
Journal Article; Article
Autor(en):
Beer, Ambros J; Schwarzenböck, Sarah M; Zantl, Niko; Souvatzoglou, Michael; Maurer, Tobias; Watzlowik, Petra; Kessler, Horst; Wester, Hans-Jürgen; Schwaiger, Markus; Krause, Bernd Joachim
Abstract:
Due to the high expression of the integrin ?v?3 not only on endothelial cells, but also on mature osteoclasts and prostate cancer cells, imaging of osseous metastases with ?v?3-targeted tracers seems promising. However, little is known about the patterns of ?v?3-expression in metastasized prostate cancer lesions in-vivo. Thus we evaluated the uptake of the ?v?3-specific PET tracer [18F]Galacto-RGD for assessment of bone metastases in prostate cancer patients.[18F]Galacto-RGD PET identified 58/74...     »
Zeitschriftentitel:
Oncotarget
Jahr:
2016
Band / Volume:
7
Heft / Issue:
19
Seitenangaben Beitrag:
28151-9
Sprache:
eng
Volltext / DOI:
doi:10.18632/oncotarget.8611
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27058620
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin; Urologische Klinik und Poliklinik
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