User: Guest  Login
Title:

First Experience with Chemokine Receptor CXCR4-Targeted PET Imaging of Patients with Solid Cancers.

Document type:
Journal Article; Article
Author(s):
Vag, Tibor; Gerngross, Carlos; Herhaus, Peter; Eiber, Matthias; Philipp-Abbrederis, Kathrin; Graner, Frank-Philipp; Ettl, Johannes; Keller, Ulrich; Wester, Hans-Jürgen; Schwaiger, Markus
Abstract:
CXCR4 is a chemokine receptor that is overexpressed in various human cancers and is involved in tumor metastasis. The aim of this proof-of-concept study was to evaluate a novel CXCR4-targeted PET probe in patients with solid cancers with reported in vitro evidence of CXCR4 overexpression and to estimate its potential diagnostic value.Twenty-one patients with histologically proven pancreatic cancer, laryngeal cancer, non-small cell lung cancer, prostate cancer, melanoma, breast cancer, hepatocell...     »
Journal title abbreviation:
J Nucl Med
Year:
2016
Journal volume:
57
Journal issue:
5
Pages contribution:
741-6
Language:
eng
Fulltext / DOI:
doi:10.2967/jnumed.115.161034
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26769866
Print-ISSN:
0161-5505
TUM Institution:
Frauenklinik und Poliklinik; III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Klinik und Poliklinik für Nuklearmedizin
 BibTeX