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Titel:

CXCR4: A New Player in an Old Scene?

Dokumenttyp:
Journal Article; Review
Autor(en):
Knopf, Andreas; Fritsche, Marie Kristin; Li, Yin
Abstract:
Transmembrane C-X-C chemokine receptor 4 (CXCR4) and its ligand C-X-C motif chemokine 12 (CXCL12) came into focus in many solid cancers, allowing a more fundamental diagnostic and therapeutic approach by modulating the immune response against cancer cells. CXCR4 and CXCL12 mediate cell proliferation, migration, and metastatic outgrowth in head and neck squamous cell carcinoma (HNSCC) and are strongly associated with cancer recurrence and patient survival. Despite recent advances in molecular ima...     »
Zeitschriftentitel:
ORL J Otorhinolaryngol Relat Spec
Jahr:
2017
Band / Volume:
79
Heft / Issue:
1-2
Seitenangaben Beitrag:
34-42
Sprache:
eng
Volltext / DOI:
doi:10.1159/000455706
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28231592
Print-ISSN:
0301-1569
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik
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