User: Guest  Login
Title:

Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats.

Document type:
Journal Article; 110
Author(s):
Altomonte, Jennifer; Muñoz-Álvarez, Kim A; Shinozaki, Katsunori; Baumgartner, Christine; Kaissis, Georgios; Braren, Rickmer; Ebert, Oliver
Abstract:
Hepatocellular carcinoma (HCC) is a disease with limited treatment options and poor prognosis. In recent years, oncolytic virotherapies have proven themselves to be potentially powerful tools to fight malignancy. Due to the unique dual blood supply in the liver, it is possible to apply therapies locally to orthotopic liver tumors, which are predominantly fed by arterial blood flow. We have previously demonstrated that hepatic arterial delivery of oncolytic viruses results in safe and efficient t...     »
Journal title abbreviation:
J Vis Exp
Year:
2016
Journal issue:
110
Language:
eng
Fulltext / DOI:
doi:10.3791/53757
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27167921
Print-ISSN:
1940-087X
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Kliniken und Institute
 BibTeX