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Title:

Rabbit models to study atherosclerosis and its complications - Transgenic vascular protein expression in vivo.

Document type:
Journal Article; Review; Review
Author(s):
Baumgartner, Christine; Brandl, Johanna; Münch, Götz; Ungerer, Martin
Abstract:
Animal models of atherosclerosis often present limitations of transferability, since important hallmarks of human disease are not completely reproduced in other species. Rabbits have been used in several approaches: 1) inbred strains: Watanabe hereditary hyperlipidemic animals which express a defect in the LDL receptor, 2) transgenic rabbits, which overexpress human lipoproteins, and first knock-out rabbits. 3) native New Zealand white rabbits (NZW) fed with cholesterol-rich diet for at least 8...     »
Journal title abbreviation:
Prog Biophys Mol Biol
Year:
2016
Journal volume:
121
Journal issue:
2
Pages contribution:
131-41
Language:
eng
Fulltext / DOI:
doi:10.1016/j.pbiomolbio.2016.05.001
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27261072
Print-ISSN:
0079-6107
TUM Institution:
Kliniken und Institute
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