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Titel:

Rabbit models to study atherosclerosis and its complications - Transgenic vascular protein expression in vivo.

Dokumenttyp:
Journal Article; Review; Review
Autor(en):
Baumgartner, Christine; Brandl, Johanna; Münch, Götz; Ungerer, Martin
Abstract:
Animal models of atherosclerosis often present limitations of transferability, since important hallmarks of human disease are not completely reproduced in other species. Rabbits have been used in several approaches: 1) inbred strains: Watanabe hereditary hyperlipidemic animals which express a defect in the LDL receptor, 2) transgenic rabbits, which overexpress human lipoproteins, and first knock-out rabbits. 3) native New Zealand white rabbits (NZW) fed with cholesterol-rich diet for at least 8...     »
Zeitschriftentitel:
Prog Biophys Mol Biol
Jahr:
2016
Band / Volume:
121
Heft / Issue:
2
Seitenangaben Beitrag:
131-41
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.pbiomolbio.2016.05.001
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27261072
Print-ISSN:
0079-6107
TUM Einrichtung:
Kliniken und Institute
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