Hypothalamic tanycytes: gatekeepers to metabolic control.
Document type:
Comment; Journal Article; Editorial Material
Author(s):
Gao, Yuanqing; Tschöp, Matthias H; Luquet, Serge
Abstract:
How circulating signals of hunger and satiety enter the brain to reach neurons that govern energy balance has long remained a matter of controversy and speculation. Balland et al. (2014) now elucidate molecular mechanisms by which a highly specialized hypothalamic glial cell regulates transport of leptin across the blood-brain barrier.