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Title:

Estrogen, astrocytes and the neuroendocrine control of metabolism.

Document type:
Journal Article; Review
Author(s):
Fuente-Martin, E; Garcia-Caceres, C; Morselli, E; Clegg, D J; Chowen, J A; Finan, B; Brinton, R D; Tschöp, M H
Abstract:
Obesity, and its associated comorbidities such as type 2 diabetes, cardiovascular diseases, and certain cancers, represent major health challenges. Importantly, there is a sexual dimorphism with respect to the prevalence of obesity and its associated metabolic diseases, implicating a role for gonadal hormones. Specifically, estrogens have been demonstrated to regulate metabolism perhaps by acting as a leptin mimetic in the central nervous system (CNS). CNS estrogen receptors (ERs) include ER alp...     »
Journal title abbreviation:
Rev Endocr Metab Disord
Year:
2013
Journal volume:
14
Journal issue:
4
Pages contribution:
331-8
Language:
eng
Fulltext / DOI:
doi:10.1007/s11154-013-9263-7
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24009071
Print-ISSN:
1389-9155
TUM Institution:
Kliniken und Institute
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