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Titel:

G-protein coupled receptor 83 (GPR83) signaling determined by constitutive and zinc(II)-induced activity.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Müller, Anne; Kleinau, Gunnar; Piechowski, Carolin L; Müller, Timo D; Finan, Brian; Pratzka, Juliane; Grüters, Annette; Krude, Heiko; Tschöp, Matthias; Biebermann, Heike
Abstract:
The G-protein coupled receptor 83 (GPR83) is an orphan G-protein coupled receptor for which the natural ligand(s) and signaling pathway(s) remain to be identified. Previous studies suggest a role of GPR83 in the regulation of thermogenesis and the control of circulating adiponectin. The aim of this study was to gain insights into the molecular underpinnings underlying GPR83 signaling. In particular, we aimed to assess the underlying G-protein activated signaling pathway of GPR83 and how this pat...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2013
Band / Volume:
8
Heft / Issue:
1
Seitenangaben Beitrag:
e53347
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0053347
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23335960
Print-ISSN:
1932-6203
TUM Einrichtung:
Kliniken und Institute
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