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Title:

A randomized trial of icatibant in ACE-inhibitor-induced angioedema.

Document type:
Clinical Trial, Phase II; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Author(s):
Ba?, Murat; Greve, Jens; Stelter, Klaus; Havel, Miriam; Strassen, Ulrich; Rotter, Nicole; Veit, Johannes; Schossow, Beate; Hapfelmeier, Alexander; Kehl, Victoria; Kojda, Georg; Hoffmann, Thomas K
Abstract:
Angioedema induced by treatment with angiotensin-converting-enzyme (ACE) inhibitors accounts for one third of angioedema cases in the emergency room; it is usually manifested in the upper airway and the head and neck region. There is no approved treatment for this potentially life-threatening condition.In this multicenter, double-blind, double-dummy, randomized phase 2 study, we assigned patients who had ACE-inhibitor-induced angioedema of the upper aerodigestive tract to treatment with 30 mg o...     »
Journal title abbreviation:
N Engl J Med
Year:
2015
Journal volume:
372
Journal issue:
5
Pages contribution:
418-25
Language:
eng
Fulltext / DOI:
doi:10.1056/NEJMoa1312524
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25629740
Print-ISSN:
0028-4793
TUM Institution:
Hals-Nasen-Ohrenklinik und Poliklinik; Institut für Medizinische Statistik und Epidemiologie; Kliniken und Institute
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