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Titel:

Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Autor(en):
Habegger, Kirk M; Al-Massadi, Omar; Heppner, Kristy M; Myronovych, Andriy; Holland, Jenna; Berger, Jose; Yi, Chun-Xia; Gao, Yuanging; Lehti, Maarit; Ottaway, Nickki; Amburgy, Sarah; Raver, Christine; Müller, Timo D; Pfluger, Paul T; Kohli, Rohit; Perez-Tilve, Diego; Seeley, Randy J; Tschöp, Matthias H
Abstract:
Surgical interventions that prevent nutrient exposure to the duodenum are among the most successful treatments for obesity and diabetes. However, these interventions are highly invasive, irreversible and often carry significant risk. The duodenal-endoluminal sleeve (DES) is a flexible tube that acts as a barrier to nutrient-tissue interaction along the duodenum. We implanted this device in Zucker Diabetic Fatty (ZDF) rats to gain greater understanding of duodenal nutrient exclusion on glucose ho...     »
Zeitschriftentitel:
Gut
Jahr:
2014
Band / Volume:
63
Heft / Issue:
8
Seitenangaben Beitrag:
1238-46
Sprache:
eng
Volltext / DOI:
doi:10.1136/gutjnl-2013-304583
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24107591
Print-ISSN:
0017-5749
TUM Einrichtung:
Kliniken und Institute
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