User: Guest  Login
Less Searchfields
Simple search
Title:

The Expression of Checkpoint and DNA Repair Genes in Head and Neck Cancer as Possible Predictive Factors.

Document type:
Journal Article
Author(s):
Rusz, Orsolya; Pál, Margit; Szilágyi, Éva; Rovó, László; Varga, Zoltán; Tomisa, Bernadett; Fábián, Gabriella; Kovács, Levente; Nagy, Olga; Mozes, Petra; Reisz, Zita; Tiszlavicz, László; Deák, Péter; Kahan, Zsuzsanna
Abstract:
DNA damage response failure may influence the efficacy of DNA-damaging treatments. We determined the expression of 16 genes involved in distinct DNA damage response pathways, in association with the response to standard therapy. Twenty patients with locoregionally advanced, squamous cell head and neck carcinoma were enrolled. The treatment included induction chemotherapy (iChT) with docetaxel, cisplatin and 5-fluorouracil followed by concomitant chemoradiotherapy (ChRT) or radiotherapy (RT) alon...     »
Journal title abbreviation:
Pathol Oncol Res
Year:
2017
Journal volume:
23
Journal issue:
2
Pages contribution:
253-264
Language:
eng
Fulltext / DOI:
doi:10.1007/s12253-016-0088-z
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27411922
Print-ISSN:
1219-4956
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
 BibTeX