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Title:

Computational modelling of the cerebral cortical microvasculature: effect of x-ray microbeams versus broad beam irradiation.

Document type:
Journal Article
Author(s):
Merrem, A; Bartzsch, S; Laissue, J; Oelfke, U
Abstract:
Microbeam Radiation Therapy is an innovative pre-clinical strategy which uses arrays of parallel, tens of micrometres wide kilo-voltage photon beams to treat tumours. These x-ray beams are typically generated on a synchrotron source. It was shown that these beam geometries allow exceptional normal tissue sparing from radiation damage while still being effective in tumour ablation. A final biological explanation for this enhanced therapeutic ratio has still not been found, some experimental data...     »
Journal title abbreviation:
Phys Med Biol
Year:
2017
Journal volume:
62
Journal issue:
10
Pages contribution:
3902-3922
Language:
eng
Fulltext / DOI:
doi:10.1088/1361-6560/aa68d5
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28333689
Print-ISSN:
0031-9155
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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