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Titel:

The Expression of Checkpoint and DNA Repair Genes in Head and Neck Cancer as Possible Predictive Factors.

Dokumenttyp:
Journal Article
Autor(en):
Rusz, Orsolya; Pál, Margit; Szilágyi, Éva; Rovó, László; Varga, Zoltán; Tomisa, Bernadett; Fábián, Gabriella; Kovács, Levente; Nagy, Olga; Mozes, Petra; Reisz, Zita; Tiszlavicz, László; Deák, Péter; Kahan, Zsuzsanna
Abstract:
DNA damage response failure may influence the efficacy of DNA-damaging treatments. We determined the expression of 16 genes involved in distinct DNA damage response pathways, in association with the response to standard therapy. Twenty patients with locoregionally advanced, squamous cell head and neck carcinoma were enrolled. The treatment included induction chemotherapy (iChT) with docetaxel, cisplatin and 5-fluorouracil followed by concomitant chemoradiotherapy (ChRT) or radiotherapy (RT) alon...     »
Zeitschriftentitel:
Pathol Oncol Res
Jahr:
2017
Band / Volume:
23
Heft / Issue:
2
Seitenangaben Beitrag:
253-264
Sprache:
eng
Volltext / DOI:
doi:10.1007/s12253-016-0088-z
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27411922
Print-ISSN:
1219-4956
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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