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Title:

Novel Monoclonal Antibodies Recognizing Human Prostate-Specific Membrane Antigen (PSMA) as Research and Theranostic Tools.

Document type:
Journal Article
Author(s):
Nováková, Zora; Foss, Catherine A; Copeland, Benjamin T; Morath, Volker; Baranová, Petra; Havlínová, Barbora; Skerra, Arne; Pomper, Martin G; Barinka, Cyril
Abstract:
Prostate-specific membrane antigen (PSMA) is a validated target for the imaging and therapy of prostate cancer. Here, we report the detailed characterization of four novel murine monoclonal antibodies (mAbs) recognizing human PSMA as well as PSMA orthologs from different species.Performance of purified mAbs was assayed using a comprehensive panel of in vitro experimental setups including Western blotting, immunofluorescence, immunohistochemistry, ELISA, flow cytometry, and surface-plasmon resona...     »
Journal title abbreviation:
Prostate
Year:
2017
Journal volume:
77
Journal issue:
7
Pages contribution:
749-764
Language:
eng
Fulltext / DOI:
doi:10.1002/pros.23311
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28247415
Print-ISSN:
0270-4137
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin
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